Dr. Pushpanathan Muthuirulan
Height is a complex trait influenced by genes and variety of environmental factors that has gained insights into the genetic architecture of common human traits and diseases. In recent years, a number of rare genetic variants have been identified in humans that are convincingly and reproducibly associated with normal height variations and growth disorders. My primary research interest is to use functional genomic approaches to understand how these genetic variants or DNA changes in human genome might affects normal gene expression pattern leading to alteration in bone growth and development. I am also interested in uncovering novel height variants or loci that close the “missing heritability” gap, whilst strengthening our knowledge on the biology of traits, evolutionary significance on human height variations and heritability of height disorders.