My lab's research is on identifying the DNA changes underlying human and non-human primate biological adaptations. In the process of identifying these changes, we seek to reveal basic developmental and genetic mechanisms governing biological trait formation and inheritance as well as their influence on disease risk. In the lab, we use a variety of tools spanning developmental biology, genetics, genomics, comparative biology, and primate/human evolution. Currently, we are focusing on two specific areas: 1) the discovery of the genetic alterations that determine the unique human post-cranial skeleton; and 2) the elucidation of the genetic and developmental architecture underlying the diversity of joint types in primates.
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